IntroductionIntroductionEpidémiologieI. Epidémiologie des calculs rénauxI.1. Prévalence des calculs rénauxI.2.Une tendance en hausse chez l’enfantPhysiopathologieII. Physiopathologie des calculs rénauxII.1. LithogenèseII.1.1. La sursaturation urinaire : moteur de la cristallogenèseII.1.2. Promoteurs et inhibiteurs de la cristallisationII.2. Volume et composition urinaire : un équilibre nécessaireFacteurs de risqueIII. Facteurs de risque de la lithiase urinaireIII.1. Facteurs de risque individuels immuablesIII.1.1 Antécédents familiauxIII.1.2. Race et origine ethniqueIII.1.3. Âge et sexeIII.1.4. Changement actuel de la prévalence en fonction du sexeIII.2. Facteurs liés au mode de vieIII.2.1. Apports en calciumIII.2.2. Facteurs de risque alimentaires émergentsIII.2.3. Association à d’autres maladies chroniquesDéshydratationIV. La déshydratation : facteur de risque des calculs rénauxIV.1. Faible volume urinaire : facteur de risque clé dans la formation de calculs rénauxIV.2. Facteurs environnementaux prédisposant à un faible volume urinaireIV.2.1. Risque de calculs rénaux en fonction de l’activité professionnelleIV.2.2. Climat et température : facteurs de risqueEau et récurrenceV. Augmentation de la consommation d’eau et prévention de la récurrence de la lithiaseV.1. Réduction du taux de récurrence par une hausse des apports hydriquesV.2. Apports hydriques et marqueurs urinaires chez le sujet formant des calculsEau et incidenceVI. Augmentation de la consommation d’eau et prévention primaire des calculsVI.1. Réduction de l’incidence des calculs par augmentation des apports hydriquesVI.2. Apports hydriques et paramètres urinaires chez le sujet sainCoûts sanitairesVII. Apports hydriques et coûts sanitaires engendrés par les calculs rénauxVII.1. Réduction des coûts de la récurrence lithiasique par des apports hydriques adéquatsVII.2. Réduction des coûts du premier épisode de lithiase par des apports hydriques adéquatsRecommandationsVIII. Recommandations alimentaires et hydriques pour la prévention de la lithiaseVIII.1. Recommandations pour la prévention de la récurrence lithiasiqueVIII.2. Recommandations alimentaires et directives sur les apports hydriques pour la population généraleConclusionConclusionRéferencesRéferences

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Amar A, Harrache-Chettouh D, Atmani F, Benali M. (2006) Beneficial effect of increasing water intake on a lithiasic population of Sidi-Bel-Abbes, West Algerian region. Journal of Chinese clinical medicine 1:315-321.


Atan L, Andreoni C, Ortiz V, Silva EK, Pitta R, Atan F, Srougi M. (2005) High kidney stone risk in men working in steel industry at hot temperatures. Urology65:858-861.


Bartoletti R, Cai T, Mondaini N, Melone F, Travaglini F, Carini M, Rizzo M. (2007) Epidemiology and risk factors in urolithiasis. Urol.Int. 79 Suppl 1:3-7.


Basiri A, Moghaddam SM, Khoddam R, Nejad ST, Hakimi A. (2004) Monthly variations of urinary stone colic in Iran and its relationship to the fasting month of Ramadan. J Pak.Med Assoc. 54:6-8.


Borghi L, Guerra A, Meschi T, Briganti A, Schianchi T, Allegri F, Novarini A. (1999a) Relationship between supersaturation and calcium oxalate crystallization in normals and idiopathic calcium oxalate stone formers. Kidney.Int. 55:1041-1050.


Borghi L, Meschi T, Amato F, Briganti A, Novarini A, Giannini A. (1996) Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study. J Urol. 155:839-843.


Borghi L, Meschi T, Amato F, Novarini A, Romanelli A, Cigala F. (1993) Hot occupation and nephrolithiasis. J Urol150:1757-1760.


Borghi L, Meschi T, Guerra A, Briganti A, Schianchi T, Allegri F, Novarini A. (1999b) Essential arterial hypertension and stone disease. Kidney.Int. 55:2397-2406.


Borghi L, Meschi T, Schianchi T, Briganti A, Guerra A, Allegri F, Novarini A. (1999c) Urine volume: stone risk factor and preventive measure. Nephron81 Suppl 1:31-37.


Boyce CJ, Garver FK, STRAWCUTTER HE. (1956) Incidence of urinary calculi among patients in general hospitals, 1948 to 1952. J Am Med Assoc 161:1437-1442.


Brenna I, Dogliotti E, Terranegra A, Raspini B, Soldati L. (2013) Nephrolithiasis: nutrition as cause or therapeutic tool. J Transl.Med 11:178.


Brenner B and Rector JRF. (2008) Nephrolithiasis. In: Brenner and Rector’s: The Kidney. Philadelphia (PA): Saunders, 1299-1349.


Brikowski TH, Lotan Y, Pearle MS. (2008) Climate-related increase in the prevalence of urolithiasis in the United States. Proc.Natl.Acad.Sci.U.S.A. 105:9841-9846.


Cameron MA, Maalouf NM, Adams-Huet B, Moe OW, Sakhaee K. (2006) Urine composition in type 2 diabetes: predisposition to uric acid nephrolithiasis. J Am.Soc.Nephrol. 17:1422-1428.


Cappuccio FP, Siani A, Barba G, Mellone MC, Russo L, Farinaro E, Trevisan M, Mancini M, Strazzullo P. (1999) A prospective study of hypertension and the incidence of kidney stones in men. J Hypertens. 17:1017-1022.


Chauhan V, Eskin B, Allegra JR, Cochrane DG. (2004) Effect of season, age, and gender on renal colic incidence. Am.J Emerg.Med 22:560-563.


Chen YK, Lin HC, Chen CS, Yeh SD. (2008) Seasonal variations in urinary calculi attacks and their association with climate: a population based study. J Urol179:564-569.


Clayton DB, Pope JC. (2011) The increasing pediatric stone disease problem. Ther.Adv.Urol3:3-12.


Coe FL, Evan A, Worcester E. (2011) Pathophysiology-based treatment of idiopathic calcium kidney stones. Clin J Am Soc. Nephrol. 6:2083-2092. 


Coe FL, Parks JH, Moore ES. (1979) Familial idiopathic hypercalciuria. N Engl J Med 300:337-340.


Curhan GC. (2007) Epidemiology of stone disease. Urol.Clin North Am 34:287-293.


Curhan GC, Taylor EN. (2008) 24-h uric acid excretion and the risk of kidney stones. Kidney.Int. 73:489-496.


Curhan GC, Willett WC, Rimm EB, Speizer FE, Stampfer MJ. (1998) Body size and risk of kidney stones. J Am Soc.Nephrol. 9:1645-1652.


Curhan GC, Willett WC, Rimm EB, Stampfer MJ. (1993) A prospective study of dietary calcium and other nutrients and the risk of symptomatic kidney stones. N Engl J Med 328:833-838.


Curhan GC, Willett WC, Rimm EB, Stampfer MJ. (1997a) Family history and risk of kidney stones. J Am Soc.Nephrol. 8:1568-1573.


Curhan GC, Willett WC, Speizer FE, Spiegelman D, Stampfer MJ. (1997b) Comparison of dietary calcium with supplemental calcium and other nutrients as factors affecting the risk for kidney stones in women. Ann.Intern.Med 126:497-504.


Curhan GC, Willett WC, Speizer FE, Stampfer MJ. (2001) Twenty-four-hour urine chemistries and the risk of kidney stones among women and men. Kidney.Int. 59:2290-2298.


Daudon M. (2005) [Epidemiology of nephrolithiasis in France]. Ann.Urol.(Paris.) 39:209-231.

Daudon M, Traxer O, Conort P, Lacour B, Jungers P. (2006) Type 2 diabetes increases the risk for uric acid stones. J Am Soc.Nephrol. 17:2026-2033.


Daudon M, Traxer O, Jungers P. (2012). Lithiase Urinaire. Paris: Lavoisier.


de La Gueronniere V, Le Bellego L, Jimenez IB, Dohein O, Tack I, Daudon M. (2011) Increasing water intake by 2 liters reduces crystallization risk indexes in healthy subjects. Arch Ital Urol Androl. 83:43-50.


Dwyer ME, Krambeck AE, Bergstralh EJ, Milliner DS, Lieske JC, Rule AD. (2012) Temporal trends in incidence of kidney stones among children: a 25-year population based study. J Urol. 188:247-252.


Embon OM, Rose GA, Rosenbaum T. (1990) Chronic dehydration stone disease. Br.J Urol. 66:357-362.


Ettinger B. (1979) Recurrence of nephrolithiasis. A six-year prospective study. Am J Med 67:245-248.


Evan AP. (2010) Physiopathology and etiology of stone formation in the kidney and the urinary tract. Pediatr Nephrol. 25:831-841.


Ferrari P, Piazza R, Ghidini N, Bisi M, Galizia G, Ferrari G. (2007) Lithiasis and risk factors. Urol.Int. 79 Suppl 1:8-15.


Finlayson B. (1978) Physicochemical aspects of urolithiasis. Kidney.Int. 13:344-360.


Fleisch H. (1978) Inhibitors and promoters of stone formation. Kidney.Int. 13:361-371.


Fletcher BA, Lin S, Fitzgerald EF, Hwang SA. (2012) Association of summer temperatures with hospital admissions for renal diseases in New York State: a case-crossover study. Am.J Epidemiol 175:907-916.


Frank M, ATSMON A, SUGAR P, De VA. (1963) Epidemiological investigation of urolithiasis in the hot arid Southern region of Israel. Urol.Int. 15:65-76.


Frank M, De VA. (1966) Prevention of urolithiasis. Education to adequate fluid intake in a new town situated in the Judean Desert Mountains. Arch.Environ.Health 13:625-630. 


Guerra A, Meschi T, Allegri F, Prati B, Nouvenne A, Fiaccadori E, Borghi L. (2006) Concentrated urine and diluted urine: the effects of citrate and magnesium on the crystallization of calcium oxalate induced in vitro by an oxalate load. Urol.Res. 34:359-364.


Hari Kumar KV, Modi KD. (2011) Analysis of risk factors for uric acid nephrolithiasis in type 2 diabetes. Saudi.J Kidney.Dis. Transpl. 22:482-487.


Hesse A, Brandle E, Wilbert D, Kohrmann KU, Alken P. (2003) Study on the prevalence and incidence of urolithiasis in Germany comparing the years 1979 vs. 2000. Eur.Urol. 44:709-713.


Hosking DH, Erickson SB, Van den Berg CJ, Wilson DM, Smith LH. (1983) The stone clinic effect in patients with idiopathic calcium urolithiasis. J Urol. 130:1115-1118.


Hughes J, Norman RW. (1992) Diet and calcium stones. CMAJ. 146:137-143.

Iguchi M, Umekawa T, Katoh Y, Kohri K, Kurita T. (1996) Prevalence of urolithiasis in Kaizuka City, Japan--an epidemiologic study of urinary stones. Int.J Urol3:175-179.


Indridason OS, Birgisson S, Edvardsson VO, Sigvaldason H, Sigfusson N, Palsson R. (2006) Epidemiology of kidney stones in Iceland: a population-based study. Scand.J Urol.Nephrol40:215-220.


Irving RA, Noakes TD, Rodgers AL, Swartz L. (1986) Crystalluria in marathon runners. 1. Standard marathon--males. Urol. Res 14:289-294.


Kaid-Omar Z, Belouatek A, Driouch A, Taleb-Bendiab H, Lacour B, Addou A, Daudon M. (2001) [Effects of diuretic therapy on spontaneous expulsion of urinary calculi, urinary pH, and crystalluria in lithiasic patients]. Prog.Urol. 11:450-457.


Kairaitis L. (2007) The CARI guidelines. Kidney stones: prevention of recurrent calcium nephrolithiasis. Nephrology. (Carlton.) 12 Suppl 1:S11-S20.


Kim H, Jo MK, Kwak C, Park SK, Yoo KY, Kang D, Lee C. (2002) Prevalence and epidemiologic characteristics of urolithiasis in Seoul, Korea. Urology59:517-521.


Lee YH, Huang WC, Tsai JY, Lu CM, Chen WC, Lee MH, Hsu HS, Huang JK, Chang LS. (2002) Epidemiological studies on the prevalence of upper urinary calculi in Taiwan. Urol.Int. 68:172-177.


Leonetti F, Dussol B, Berthezene P, Thirion X, Berland Y. (1998) Dietary and urinary risk factors for stones in idiopathic calcium stone formers compared with healthy subjects. Nephrol.Dial.Transplant. 13:617-622.


Lopez M, Hoppe B. (2010) History, epidemiology and regional diversities of urolithiasis. Pediatr Nephrol25:49-59.


Lotan Y, Buendia J, I, Lenoir-Wijnkoop I, Daudon M, Molinier L, Tack I, Nuijten MJ. (2012) Primary prevention of nephrolithiasis is cost-effective for a national healthcare system. BJU.Int. 110:E1060-E1067.


Lotan Y, Buendia J, I, Lenoir-Wijnkoop I, Daudon M, Molinier L, Tack I, Nuijten MJ. (2013) Increased water intake as a prevention strategy for recurrent urolithiasis: major impact of compliance on cost-effectiveness. J Urol189:935-939.


Madore F, Stampfer MJ, Willett WC, Speizer FE, Curhan GC. (1998) Nephrolithiasis and risk of hypertension in women. Am J Kidney.Dis32:802-807.


Marickar YM, Vijay A. (2009) Female stone disease: the changing trend. Urol.Res. 37:337-340.

Milvy P, Colt E, Thornton J. (1981) A high incidence of urolithiasis in male marathon runners. J Sports Med Phys.Fitness 21:295-298.


Muslumanoglu AY, Binbay M, Yuruk E, Akman T, Tepeler A, Esen T, Tefekli AH. (2011) Updated epidemiologic study of urolithiasis in Turkey. I: Changing characteristics of urolithiasis. Urol.Res. 39:309-314. 


Orakzai N, Hanbury DC, Farrington K. (2004) Screening for biochemical abnormalities in urolithiasis patients. J Ayub.Med Coll.Abbottabad. 16:60-63.


Pak CY, Sakhaee K, Crowther C, Brinkley L. (1980) Evidence justifying a high fluid intake in treatment of nephrolithiasis. Ann.Intern.Med 93:36-39.


Pearle MS, Calhoun EA, Curhan GC. (2005) Urologic diseases in America project: urolithiasis. J Urol. 173:848-857.

Peres LA, Molina AS, Galles MH. (2003) Metabolic investigation of patients with urolithiasis in a specific region. Int.Braz.J Urol. 29:217-220.


Pinduli I, Spivacow R, del VE, Vidal S, Negri AL, Previgliano H, Farias ER, Andrade JH, Negri GM, Boffi-Boggero HJ. (2006) Prevalence of urolithiasis in the autonomous city of Buenos Aires, Argentina. Urol.Res34:8-11.


Ramello A, Vitale C, Marangella M. (2000) Epidemiology of nephrolithiasis. J Nephrol. 13 Suppl 3:S45-S50.


Rodgers AL, Greyling KG, Noakes TD. (1991) Crystalluria in marathon runners. III. Stone-forming subjects. Urol.Res 19:189-192.


Ross AC, Taylor CL, Yaktine AL, Del Valle HB. (2011) Dietary Reference Intakes for Calcium and Vitamin D. National Academies Press (Washington DC).


Safarinejad MR. (2007) Adult urolithiasis in a population-based study in Iran: prevalence, incidence, and associated risk factors. Urol.Res. 35:73-82.


Sarica K, Eryildirim B, Yencilek F, Kuyumcuoglu U. (2009) Role of overweight status on stone-forming risk factors in children: a prospective study. Urology73:1003-1007.


Sarica K, Inal Y, Erturhan S, Yagci F. (2006) The effect of calcium channel blockers on stone regrowth and recurrence after shock wave lithotripsy. Urol.Res 34:184-189.


Sas DJ. (2011) An update on the changing epidemiology and metabolic risk factors in pediatric kidney stone disease. Clin.J Am.Soc.Nephrol. 6:2062-2068.


Sas DJ, Hulsey TC, Shatat IF, Orak JK. (2010) Increasing incidence of kidney stones in children evaluated in the emergency department. J Pediatr 157:132-137.


Scales CD, Jr., Curtis LH, Norris RD, Springhart WP, Sur RL, Schulman KA, Preminger GM. (2007) Changing gender prevalence of stone disease. J Urol. 177:979-982.


Scales CD, Jr., Smith AC, Hanley JM, Saigal CS. (2012) Prevalence of kidney stones in the United States. Eur.Urol. 62:160-165.


Sepahi MA, Heidari A, Shajari A. (2010) Clinical manifestations and etiology of renal stones in children less than 14 years age. Saudi.J Kidney.Dis.Transpl. 21:181-184.


Serio A, Fraioli A. (1999) Epidemiology of nephrolithiasis. Nephron81 Suppl 1:26-30.


Shah J, Whitfield HN. (2002) Urolithiasis through the ages. BJU.Int. 89:801-810.


Siener R, Glatz S, Nicolay C, Hesse A. (2004) The role of overweight and obesity in calcium oxalate stone formation. Obes. Res. 12:106-113.


Soucie JM, Coates RJ, McClellan W, Austin H, Thun M. (1996) Relation between geographic variability in kidney stones prevalence and risk factors for stones. Am.J Epidemiol 143:487-495.


Soucie JM, Thun MJ, Coates RJ, McClellan W, Austin H. (1994) Demographic and geographic variability of kidney stones in the United States. Kidney.Int. 46:893-899. 


Stamatelou KK, Francis ME, Jones CA, Nyberg LM, Curhan GC. (2003) Time trends in reported prevalence of kidney stones in the United States: 1976-1994. Kidney.Int. 63:1817-1823.


Stamatiou KN, Karanasiou VI, Lacroix RE, Kavouras NG, Papadimitriou VT, Chlopsios C, Lebren FA, Sofras F. (2006) Prevalence of urolithiasis in rural Thebes, Greece. Rural.Remote.Health 6:610.


Stitchantrakul W, Kochakarn W, Ruangraksa C, Domrongkitchaiporn S. (2007) Urinary risk factors for recurrent calcium stone formation in Thai stone formers. J Med Assoc.Thai. 90:688-698.


Strope SA, Wolf JS, Jr., Hollenbeck BK. (2010) Changes in gender distribution of urinary stone disease. Urology75:543-6, 546.


Sutherland JW, Parks JH, Coe FL. (1985) Recurrence after a single renal stone in a community practice. Miner.Electrolyte. Metab 11:267-269.


Taylor EN, Stampfer MJ, Curhan GC. (2005) Obesity, weight gain, and the risk of kidney stones. JAMA293:455-462.


Thomas BG. (2010) Management of stones in childhood. Curr Opin Urol. 20:159-162.


Tiselius HG. (1991) Aspects on Estimation of the Risk of Calcium Oxalate Crystallization in Urine. Urologia Internationalis 47:255-259.


Tiselius HG, Ackermann D, Alken P, Buck C, Conort P, Gallucci M. (2001) Guidelines on urolithiasis. Eur Urol. 40:362-371.


Trinchieri A, Cappoli S, Esposito N, Acquati P. (2008) Epidemiology of renal colic in a district general hospital. Arch.Ital.Urol. Androl. 80:1-4.


World Health Organization (. (2007) Protein and amino acid requirements in human nutrition. World Health Organ.Tech Rep.Ser. 1-265.


World Health Organization (. (2012) Guideline: Sodium Intake for Adults and Children. 

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